Virology
September 9, 2020

Virology Placeholder post

(Poster presented at AACR-NCI-EORTC Meeting on Saturday, Nov 7, 2015)
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NASH
August 27, 2020

Novel, first-in-class, fatty acid synthase inhibitor, TVB-2640 versus placebo demonstrates clinically significant reduction in liver fat by MRI-PDFF in NASH

(Oral presentation, EASL International Liver Congress, 27-29 August 2020, Abstract #AS074)
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NASH
August 27, 2020

The FASN inhibitor TVB-2640 is efficacious in a new 3D human liver microtissue model of NASH

(Poster, EASL International Liver Congress, 27-29 August 2020, Abstract #SAT038)
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NASH
December 18, 2019

First‐in‐class fatty acid synthase inhibitor TVB‐2640 reduces hepatic de novo lipogenesis in males with metabolic abnormalities

(Paper, Hepatology 2020)
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NASH
September 6, 2019

Fibroblast Growth Factor-21 and its Relationship to Human Liver Fat Synthesis; Impact of a New Therapeutic Agent

(Poster, Obesity Week, 11-15 November 2018, Abstract # T-P-3383)
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NASH
September 5, 2019

The FASN inhibitor, TVB3664, Ameliorates NASH in a Murine Model

(Poster, AASLD The Liver Meeting, 9-13 November 2018, Abstract #734)
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NASH
September 3, 2019

Updated Results from a Prospective Phase 2 Study in Patients with First Relapse of High-grade Astrocytoma Using TVB-2640 in Combination with bevacizumab

(Poster, ASCO Annual Meeting, 31 May – 4 June 2019, Abstract #2064)
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NASH
February 13, 2018

Progressive Reductions in Hepatic DNL with Increasing Doses of TVB-2640, a First-in-Class Pharmacologic Inhibitor of FASN

(Presented at the Keystone Symposium on Organ Crosstalk in Obesity and NAFLD, Jan. 21-25, 2018 Keystone, CO, Poster #3028)
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Oncology
October 23, 2017

Fatty Acid Synthase Inhibitor TVB-3664 Reverses Multiple Components of Diet Induced Nonalcoholic Steatohepatitis in Mice Treated With or Without Co-Administered Pirfenidone and Reduces Collagen Accumulation in Bleomycin-Induced Murine Skin Fibrosis.

(Presented at The Liver Meeting 2017®, Washington, DC, Oct 20-24, Presidential Poster of Distinction, Abstract #1994)
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Oncology
October 23, 2017

Pharmacologic Inhibition of FASN Reverses Diet-Induced Steatohepatitis in Mice and Inhibits Lipogenesis in Humans.

(Presented at The Liver Meeting 2017®, Washington, DC, Oct 20-24, Abstract #1972)
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