PRESS RELEASES
07/2021

Published Results from Sagimet’s FASCINATE-1 Phase 2a Trial Demonstrate FASN Inhibitor TVB-2640’s Ability to Significantly Reduce Excess Liver Fat

San Mateo, California, July 26, 2021 – Sagimet Biosciences Inc., a clinical-stage biotechnology company focused on developing a portfolio of internally-discovered, selective fatty acid synthase (FASN) inhibitors, announced today that Gastroenterology…
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NASH
07/2021

TVB-2640 (FASN inhibitor) for the treatment of nonalcoholic steatohepatitis: FASCINATE-1, a randomized, placebo-controlled Ph2a trial

Gastroenterology
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PRESS RELEASES
05/2021

Sagimet Biosciences Appoints Life Sciences Industry Veteran Elizabeth Grammer to Board of Directors

San Mateo, California, May 3, 2021 – Sagimet Biosciences, a clinical-stage biotechnology company focused on developing a portfolio of internally-discovered, selective fatty acid synthase (FASN) inhibitors, announced today the appointment of…
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PRESS RELEASES
04/2021

Sagimet to Present Phase 2 Data on Lead Candidate TVB-2640 at The International Liver Congress™ 2021 (EASL)

San Mateo, California, April 23, 2021 – Sagimet Biosciences, a clinical-stage biotechnology company focused on developing a portfolio of internally-discovered, selective fatty acid synthase (FASN) inhibitors, announced today that additional clinical…
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Oncology
04/2021

First-in-human study of the safety, pharmacokinetics, and pharmacodynamics of first-in-class fatty acid synthase inhibitor TVB-2640 alone and with a taxane in advanced tumors

EClinicalMedicine
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PRESS RELEASES
03/2021

Sagimet Biosciences Receives Fast Track Designation from U.S. Food and Drug Administration for FASN Inhibitor TVB-2640 in NASH

In a recent Phase 2a trial, TVB-2640 improved serum biomarkers of liver injury in patients with nonalcoholic steatohepatitis (NASH)  San Mateo, California, March 16, 2021 – Sagimet Biosciences Inc., a…
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PRESS RELEASES
03/2021

Sagimet Biosciences Names Dr. Eduardo Bruno Martins as Chief Medical Officer

Dr. Martins Joins the Company to Help Advance Sagimet’s Pipeline of FASN Inhibitors  San Mateo, California, March 11, 2021 – Sagimet Biosciences Inc., a clinical-stage biotechnology company focused on developing…
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PRESS RELEASES
03/2021

FASN Inhibitor ASC40 Demonstrates Positive Phase 2 Topline Clinical Results from China Cohort of Patients with NASH

– Oral FASN inhibitor ASC40 shown to meaningfully reduce liver fat with a 50% responder rate – Consistent improvement in biomarkers of liver inflammation as observed in U.S. cohort Shanghai,…
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PRESS RELEASES
02/2021

Sagimet Biosciences Raises $80 Million in Crossover Financing

Altium Capital, HM Capital, Invus, and PFM Health Sciences join previous investors Ascletis, Kleiner Perkins, New Enterprise Associates, Rock Springs Capital, and two undisclosed leading public equity healthcare investors in…
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PRESS RELEASES
11/2020

ASC40 (TVB-2640) Phase 2 NASH Trial Completed Patient Enrollment in China

Shanghai, China and San Francisco, California, United States, November 19,2020 – Gannex Pharma Co., Ltd., a wholly owned company of Ascletis Pharma Inc. (HKEX:1672) and Sagimet Biosciences Inc. jointly announced…
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