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Author name: Graviton

NASH, PUBLICATIONS

Denifanstat, a Fatty Acid Synthase Inhibitor, Increased Circulating Polyunsaturated Triglycerides and Decreased LDL-Cholesterol in MASH Patients with Advanced Fibrosis

By Graviton / 02/2025

Keystone Symposia

NASH, PUBLICATIONS

Denifanstat, a Fatty Acid Synthase Inhibitor, Increased Circulating Polyunsaturated Triglycerides and Decreased LDL-Cholesterol in MASH Patients with Advanced Fibrosis in a Post-Hoc Analysis of FASCINATE-2 Study

By Graviton / 02/2025

Keystone Symposia

NASH, PUBLICATIONS

FASN inhibitor

By Graviton / 01/2025

MASH TAG

NASH, PUBLICATIONS

Denifanstat showed anti-fibrotic effect both on conventional and digital pathology in a metabolic dysfunction-associated steatohepatitis (MASH) Phase 2b trial (FASCINATE-2)

By Graviton / 01/2025

MASH TAG

NASH, PUBLICATIONS

AI-Based Digital Pathology Shows that Denifanstat Improves Multiple Parameters of Fibrosis and Reduces Progression to Cirrhosis in MASH patients with F2/F3

By Graviton / 11/2024

AASLD The Liver Meeting

NASH, PUBLICATIONS

Denifanstat significantly improves liver fibrosis in difficult-to-treat MASH patients – Results from conventional and AI-based pathology from the phase 2b FASCINATE-2, a 52-week randomized, double-blind, placebo-controlled trial

By Graviton / 11/2024

AASLD The Liver Meeting

NASH, PUBLICATIONS

Fatty acid synthase (FASN) inhibitor reduces atherosclerosis development in diet-induced dyslipidaemia LDL receptor knockout mice with MASH

By Graviton / 11/2024

AASLD The Liver Meeting

NASH, PUBLICATIONS

Denifanstat for the treatment of metabolic dysfunction-associated steatohepatitis: a multicentre, double-blind, randomised, placebo-controlled, phase 2b trial

By Graviton / 10/2024

The Lancet Gastroenterology & Hepatology

NASH, Oncology, PUBLICATIONS, Virology

Demonstrating denifanstat’s differentiated approach in MASH with mechanistic and clinical data showing direct anti-fibrotic activity

By Graviton / 09/2024

8th Annual MASH Drug Development Summit

Evaluation of FASN inhibitor & GLP-1 Combination in Preclinical Mouse Model

By Graviton / 11/2023

7th Obesity and NASH Drug Development Summit

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About
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