Oncology 02/2016 Sebum Analysis from Dose Escalation and Expansion Phases of the FASN Inhibitor TVB-2640 Phase 1 Trial, A Non-Invasive Biomarker of Target Engagement Keystone Symposium - New Frontiers in Understanding Tumor Metabolism Graviton Love4
Oncology 02/2016 Sebum Analysis from Dose Escalation and Expansion Phases of the FASN Inhibitor TVB-2640 Phase 1 Trial, A Non-Invasive Biomarker of Target Engagement Keystone Symposium - New Frontiers in Understanding Tumor Metabolism Graviton Love4
Virology 12/2015 Direct Inhibition of Cellular Fatty Acid Synthase Impairs Replication of Respiratory Synctial Virus and Other Respiratory Viruses PLOS ONE natalia Love5
Oncology 11/2015 A First in Human Study of the First in Class Fatty Acid Synthase (FASN) Inhibitor TVB-2640. Results of Dose Escalation in Mono and Combination and Evidence of Preliminary Activity EORTC-NCI-AACR International Conference Graviton Love4
Oncology 11/2015 Biomarker Analyses from Dose Escalation and Expansion Phases of FASN Inhibitor TVB-2640 Phase 1 Study Shows Target Engagement in Solid Tumor Patients EORTC-NCI-AACR International Conference Graviton Love4
Oncology 11/2015 FASN inhibition studies in preclinical tumor models identify biomarkers that align with in vitro and in vivo sensitivity to TVB-2640 EORTC-NCI-AACR International Conference Graviton Love4
Oncology 07/2015 Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression EBioMedicine Graviton Love4
Oncology 06/2015 Translational Studies of a First-in-class FASN Inhibitor, TVB-2640, Linking Preclinical Studies to Clinical Laboratory Observations in Solid Tumor Patients AACR Special Conference: Metabolism and Cancer Graviton Love4
Oncology 06/2015 First-in-Human Investigation of the Oral First-in-Class Fatty Acid Synthase (FASN) Inhibitor, TVB-2640 ASCO Annual Meeting natalia Love6
Oncology 04/2015 Diacylglycerol Metabolism and Signaling Is a Driving Force Underlying FASN Inhibitor Sensitivity in Cancer Cells ACS Chemical Biology Graviton Love5