NASHPUBLICATIONS 06/2024 Denifanstat, a fatty acid synthase (FASN) inhibitor, shows significant fibrosis improvement and MASH resolution in FASCINATE-2, a Ph2b 52 week global, randomized, double blind, placebo-controlled trial in patients with F2 or F3 fibrosis EASL International Liver Congress charlie maddox Love0
NASH 11/2023 Evaluation of FASN inhibitor & GLP-1 Combination in Preclinical Mouse Model 7th Obesity and NASH Drug Development Summit Graviton Love0
NASH 06/2023 Denifanstat, a fatty acid synthase (FASN) inhibitor for the treatment of biopsy-proven NASH: A 26-week interim analysis of the FASCINATE-2 Phase 2b trial EASL International Liver Congress Lehi Vidigal Love0
NASH 11/2022 Correlation between AI-based digital pathology and non-invasive tests (NITs) – baseline data from the FASCINATE-2 phase 2b clinical study of denifanstat in patients with F2/F3 NASH AASLD The Liver Meeting Graviton Love0
NASH 11/2021 TVB-2640, a novel, first-in-class, fatty acid synthase (FASN) inhibitor: biomarker and metabolomic correlations with clinical MRI-PDFF response NASH Summit Graviton Love9
NASH 11/2021 Novel, first-in-class, fatty acid synthase (FASN) inhibitor TVB-2640 demonstrates robust clinical efficacy and safety in a global phase 2 randomized placebo-controlled NASH trial (FASCINATE-1) conducted in the U.S. and China AASLD The Liver Meeting Graviton Love9
NASH 09/2021 Translation of FASN Inhibitor TVB-2640 from Preclinical MOA to Clinical POC in NASH NASH and Fibrosis Conference Graviton Love9
NASH 11/2020 Novel, first-in-class, fatty acid synthase inhibitor, TVB-2640 versus placebo demonstrates clinically significant reduction in liver fat by MRI-PDFF in NASH AASLD Graviton Love9
Oncology 09/2020 TVB-2640 with Bevacizumab in Relapsed High-grade Astrocytoma European Society for Medical Oncology (ESMO) Congress Graviton Love9
NASH 08/2020 Novel, first-in-class, fatty acid synthase inhibitor, TVB-2640 versus placebo demonstrates clinically significant reduction in liver fat by MRI-PDFF in NASH EASL International Liver Congress Graviton Love9