OncologyUpdated results from a prospective, randomized phase 2 study in patients with first relapse of high-grade astrocytoma using TVB-2640 in combination with Avastin versus Avastin alone By natalia / 11/2018 Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology
NASHProgressive Reductions in Hepatic DNL with Increasing Doses of TVB-2640, a First-in-Class Pharmacologic Inhibitor of FASN By Graviton / 01/2018 Keystone Symposium on Organ Crosstalk in Obesity and NAFLD
OncologyFatty acid synthase inhibitor TVB-3664 reverses multiple components of diet-induced nonalcoholic steatohepatitis in mice treated with or without co-administered pirfenidone and reduces collagen accumulation in bleomycin-induced murine skin fibrosis By Graviton / 10/2017 AASLD
NASHPharmacologic Inhibition of FASN Reverses Diet-Induced Steatohepatitis in Mice and Inhibits Lipogenesis in Humans. By Graviton / 10/2017 AASLD
NASHEstablishing the foundation for a novel, first-in-class, fatty acid synthase inhibitor, TVB-2640, for the treatment of NASH By Graviton / 04/2017 EASL International Liver Congress
OncologyHeavily Pre-Treated Breast Cancer Patients show Promising Responses in the First in Human Study of the First-In-Class Fatty Acid Synthase (FASN) Inhibitor, TVB-2640 in Combination with Paclitaxel By Graviton / 12/2016 San Antonio Breast Cancer Symposium
NASHPharmacological inhibition of FASN Prevents High Fat Diet Induced Liver Damage in Mice and Significantly Reduces de novo Lipogenesis in Humans By Graviton / 11/2016 AASLD The Liver Meeting
OncologyPreliminary Activity in the First in Human Study of the First-In-Class Fatty Acid Synthase Inhibitor, TVB-2640 By Graviton / 11/2016 NCRI Cancer Conference
OncologyPreliminary Activity in the First in Human Study of the First-In-Class Fatty Acid Synthase (FASN) Inhibitor, TVB-2640 By Graviton / 06/2016 ASCO Annual Meeting